| Event Type | Event Name | Opponent(s) | |||
|---|---|---|---|---|---|
| Cypress Lake (Fort Myers) | Football (11 man) | 08/20/2021 | Preseason Classic | Kickoff Classic | Dunbar (Fort Myers) |
| Hollins (St. Petersburg) | Football (11 man) | 08/20/2021 | Preseason Classic | Pre-Season Classic | Dunedin |
| Palm Harbor University | Football (11 man) | 08/20/2021 | Preseason Classic | Pre-Season Classic | Strawberry Crest (Dover), Palm Harbor University |
| Lakeland Christian | Football (11 man) | 08/20/2021 | Preseason Classic | Kick-Off Classic | Deltona, Lakeland Christian |
| Island Coast (Cape Coral) | Football (11 man) | 08/20/2021 | Preseason Classic | Preseason Classic | Port Charlotte |
| Creekside (St. Johns) | Football (11 man) | 08/20/2021 | Preseason Classic | Creekside vs Fletcher | Fletcher (Neptune Beach), Creekside (St. Johns) |
| Kathleen (Lakeland) | Football (11 man) | 08/20/2021 | Preseason Classic | Kickoff Classic | East Bay (Gibsonton), Kathleen (Lakeland) |
| Land O Lakes | Football (11 man) | 08/20/2021 | Preseason Classic | Kick Off Classic vs Hudson | Hudson, Land O Lakes |
| Miramar | Football (11 man) | 08/20/2021 | Preseason Classic | pre-season classic | Miami Edison, Miramar |
| Crystal River | Football (11 man) | 08/20/2021 | Preseason Classic | Preseason Classic | New Smyrna Beach, Crystal River |
| Lakewood Ranch (Bradenton) | Football (11 man) | 08/20/2021 | Preseason Classic | Kick off classic | Alonso (Tampa), Lakewood Ranch (Bradenton) |
| Armwood (Seffner) | Football (11 man) | 08/20/2021 | Preseason Classic | Football Classic | Washington (Miami) |
| Mariner (Cape Coral) | Football (11 man) | 08/20/2021 | Preseason Classic | Preseason Classic | Gateway (Fort Myers) |
| Cocoa Beach | Football (11 man) | 08/20/2021 | Preseason Classic | Kick Off Classic | Mulberry, Cocoa Beach |
| Vero Beach | Football (11 man) | 08/20/2021 | Preseason Classic | Kick off Classic | Rockledge, Vero Beach |
| Martin County (Stuart) | Football (11 man) | 08/20/2021 | Preseason Classic | 2021 Kickoff Classic | Eau Gallie (Melbourne), Martin County (Stuart) |
| Immokalee | Football (11 man) | 08/20/2021 | Preseason Classic | Football Classic | Gateway Charter (Fort Myers), Immokalee |